Sleep loss may cause brain damage

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Discussion Overview

The discussion centers around the implications of sleep loss on brain health, particularly in relation to new research suggesting potential brain damage from long-term sleep deprivation. Participants explore the effects of sleep deprivation on various organisms, including humans and fruit flies, and consider the broader implications for workplace policies regarding sleep and health.

Discussion Character

  • Exploratory
  • Debate/contested
  • Conceptual clarification

Main Points Raised

  • Some participants reference research indicating that sleep deprivation may lead to lasting brain injury, challenging the notion that sleep debt can be fully repaid.
  • One participant supports the restorative theory of sleep, suggesting that sleep serves critical maintenance functions.
  • There is a question about whether short naps can mitigate the negative effects of sleep deprivation, with some uncertainty about their effectiveness.
  • Another participant notes that companies may intuitively recognize the harmful effects of sleep deprivation and have begun to implement policies to address it, though the effectiveness of such policies remains uncertain.
  • Participants mention the accumulation of metabolic waste in the brain due to sleep deprivation, referencing studies conducted on mice.

Areas of Agreement / Disagreement

Participants express a general agreement on the harmful effects of sleep deprivation, but there is no consensus on the mechanisms of damage, the effectiveness of short naps, or the implications for workplace policies.

Contextual Notes

Some claims rely on specific studies that may have limitations or assumptions not fully explored in the discussion. The effectiveness of proposed solutions, such as short naps or workplace policies, remains unresolved.

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Shift workers beware: Sleep loss may cause brain damage, new research says
http://www.cnn.com/2014/03/19/health/sleep-loss-brain-damage/index.html?hpt=hp_t2

Are you a truck driver or shift worker planning to catch up on some sleep this weekend?
Cramming in extra hours of shut-eye may not make up for those lost pulling all-nighters, new research indicates.
The damage may already be done -- brain damage, that is, said neuroscientist Sigrid Veasey from the University of Pennsylvania.
Alzheimer's & Sleep
The widely held idea that you can pay back a sizeable "sleep debt" with long naps later on seems to be a myth, she said in a study published this week in the Journal of Neuroscience.
Long-term sleep deprivation saps the brain of power even after days of recovery sleep, Veasey said. And that could be a sign of lasting brain injury.
 
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Not surprising to me. I subscribe to the restorative theory of sleep.

http://www.nature.com/nrn/journal/v14/n6/images/nrn3494-f2.jpg
 
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Indeed not that surprising: even fruit flies suffer from sleep deprivation. Great research though, the big question is now: how can damage be prevented? Could short naps be sufficient to counter negative effects?
 
Monique said:
Indeed not that surprising: even fruit flies suffer from sleep deprivation. Great research though, the big question is now: how can damage be prevented? Could short naps be sufficient to counter negative effects?

Longer term overnight trafficking processes suggest to me that there would be some maintenance processes that require a sufficient amount of time. Whether or not they're important to prevention of tissue damage I'm not sure:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564590/figure/F8/
 
Interesting, some companies it seems to me intuitively know that sleep deprivation is harmful to workers and thus considered it in their policy like shift rotation, maximum 12- hour duty and multiple/flexible day-offs. If proven on human specimen, perhaps such aforementioned company policy will be enacted into labor laws? Maybe not.

Sleep deprivation also causes accumulation of metabolic waste in the brain of mice specimen... http://www.kurzweilai.net/how-the-brain-takes-out-the-trash-while-we-sleep/comment-page-1
 

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