Telomerase Breakdown: How Does the Body Break It Down?

[EpiGen]

So I've finished my university's genetics class and we talked about how telomerase is present in a human early in life but then it disappears. Does anyone here how exactly the body breaks it down? Is there a specific chemical released throughout the body that causes it to degrade?

 

[Skrambles]

If I remember correctly, during mitosis the telomerase on each chromosome is split equally between the two daughter cells, so each one has only half as much as the original cell. During meiosis there is some mechanism that builds the telomerase back up so the fertilized embryo begins development with enough that it can keep dividing normally. A lot of research into anti-aging drugs has targeted telomerase, but I believe those drugs also increased the risk of cancer.