The road trip from South Carolina to Arizona and Southern California includes stops in Georgia, Alabama, and New Orleans, with a focus on scenic routes rather than Interstates. Highlights include visiting Tuskegee University, taking a ferry at Mobile Bay, and exploring the Gulf Coast towns affected by Hurricane Katrina. In New Orleans, the traveler enjoyed the local music scene and streetcars, while also noting the city's recovery post-disaster. The journey continued through Texas, with stops in Johnson City and Van Horn, before reaching Tucson, where family business and sightseeing were prioritized. Due to foot swelling from travel, the Southern California portion of the trip was ultimately omitted.