Kinetic energy can depend explicitly on time within the Lagrangian formulation if the inertial Cartesian coordinates are functions of generalized coordinates that also vary with time. This scenario typically arises in non-inertial reference frames. The relationship is established through the time derivative of position, which incorporates both the generalized coordinates and their time derivatives. Consequently, the expression for kinetic energy becomes explicitly time-dependent. This highlights the complexity of kinetic energy in non-inertial frames within Lagrangian mechanics.