Hello geoduck,
good question! In fact, a naive attempt at generalization of the relation
[tex]
\Delta p_x \Delta x >= \hbar/2 *[/tex]
would be
[tex]
\Delta E \Delta t >= \hbar/2, **[/tex]
which would be in fact the exact opposite of what one would want if he wanted to explain creation of short-lived particles. You are right that the opposite sign would make much more sense.
However, I would like to say that neither of these relations for energy and time
make much sense. The situation is entirely different from that of momentum and position.
The derivation of * cannot be directly applied to derive ** for energy and time, because the time is not an operator and there is no analogous commutation relation between the energy and time.
This is because in non-relativistic wave mechanics, coordinates and momenta of particles play very different role from that of time variable.
Coordinate and its conjugated momentum have associated non-commuting operators, but there is no such couple of conjugated operators for energy and time variables.
Time is just an independent variable that has nothing to do with any special particle. Although the energy can have nonzero standard deviation for some psi function, the time is the time, always with zero standard deviation. It is common for the whole description and is not influenced by anything. The statistics and averaging are only in particle properties.
So if we wanted to write the relation down anyway, we would have to write
[tex]
\Delta E \Delta t = 0,[/tex]
because
[tex]
\Delta t = 0.[/tex]
Some people like to use relations like [itex]\Delta x \Delta p \approx h[/itex] to find numbers when they cannot or are lazy to really derive or calculate from the theory.
One has to be careful not to believe in such fairy-tales too much.