What is anode break excitation in neurons?

[thrillhouse86]

Hey,

Can someone point me in the direction (or just explain to me!) the idea of Anode Break excitation in neuroscience ?

Thanks

 

[Kglocc]

I found a good description here - http://www.neuron.yale.edu/phpBB/viewtopic.php?f=26&t=360

My understanding is that while the anode is on it causes hyperpolarization, turning off the anode (a break in the stimulus) causes a depolarization rebound that triggers the action potential

 

[thrillhouse86]

thanks Kglocc,

I also stumbled across this youtube video which gives an example (but not an explanation) of Anode Break Excitation.

http://www.youtube.com/watch?v=PUQBfG9A2Ng&feature=related

 

[Kglocc]

http://www.youtube.com/watch?v=PUQBfG9A2Ng&feature=related[/QUOTE]

good informative video. old school for the win