In 3D, it would be somthing like : if you have a closed, simply-connected surface, then it is more or less a sphere. For lay(wo)man's vocabulary : simply-connected means that if you put a a rope and closed it on your surface, you can reduce it to a point, e.g. on a donut you quickly see there are possiblities such that you cannot tight the rope without breaking the donut, if you really want your rope to become a point like object (ideally). However, it is not known in 4 dimension if this is true for what is sometimes called a 3-sphere : the generalization of a sphere surface (you have 2 angles to parametrize everypoint on a sphere) to three dimension (three such angles, which is, i heard, quite hard to visualize or intuitiv. understand). However, I think it was proven that for higher dimensions this was true, so that for not mixing : for 2,-,4,5...dimensional varieties (number of free parameter on your object), this was true : i.e. the shape is deformable to a n-sphere if it has some properties like closedness and simple-connectedness...but Poincaré made at first wrong assumptions and corrected himself his mistake, but could solve after it...Technically it's quite complicated, with Homology and Homotopy groups, and other math. stuff..(which i personnally don't know even only the surface of those concepts)