Unpacking the Complexity of Human DNA

AI Thread Summary
Chimpanzees and humans share approximately 99% of their DNA, suggesting that the differences in the remaining 1% are significant in defining human traits. The discussion highlights that the simplistic view of genes having fixed functions is outdated; instead, genes can produce various protein products and function within complex regulatory networks. This complexity in gene expression plays a crucial role in differentiating species. Additionally, the presence of about 2% Neanderthal DNA in modern humans raises questions about genetic contributions from extinct relatives and their impact on human evolution. Understanding these genetic nuances is essential for comprehending the distinct characteristics that separate humans from other primates.
moriah
Messages
54
Reaction score
11
TL;DR Summary
Supposedly, chimpanzees and humans share 99% of DNA. Does this mean that it is 1% of our DNA that delineates us from them? Also, how does this figure with the 2% of neanderthal DNA that most humans today have?
What is in our DNA that separates us from other primates?
 
Biology news on Phys.org
moriah said:
Summary:: Supposedly, chimpanzees and humans share 99% of DNA. Does this mean that it is 1% of our DNA that delineates us from them? Also, how does this figure with the 2% of neanderthal DNA that most humans today have?

What is in our DNA that separates us from other primates?
You should google both of those factoids/questions to start. The numbers should be more precise. And your main question is pretty vague. I mean, you can see a lot of the similar and different traits, right?
 
I think the idea that each gene has a predictable and discrete function is a bit dated now, finding the same genes in different species doesn't necessarily mean they are doing the same thing. Many genes are capable of producing a number of protein products and operate in a regulatory network, It's how and when genes are expressed that produce the genotype. Genes provide information on relatedness but relatively small differences can lead to quite marked differences.
https://www.frontiersin.org/articles/10.3389/fmolb.2018.00020/full
 
Deadly cattle screwworm parasite found in US patient. What to know. https://www.usatoday.com/story/news/health/2025/08/25/new-world-screwworm-human-case/85813010007/ Exclusive: U.S. confirms nation's first travel-associated human screwworm case connected to Central American outbreak https://www.reuters.com/business/environment/us-confirms-nations-first-travel-associated-human-screwworm-case-connected-2025-08-25/...
Chagas disease, long considered only a threat abroad, is established in California and the Southern U.S. According to articles in the Los Angeles Times, "Chagas disease, long considered only a threat abroad, is established in California and the Southern U.S.", and "Kissing bugs bring deadly disease to California". LA Times requires a subscription. Related article -...
I am reading Nicholas Wade's book A Troublesome Inheritance. Please let's not make this thread a critique about the merits or demerits of the book. This thread is my attempt to understanding the evidence that Natural Selection in the human genome was recent and regional. On Page 103 of A Troublesome Inheritance, Wade writes the following: "The regional nature of selection was first made evident in a genomewide scan undertaken by Jonathan Pritchard, a population geneticist at the...
Back
Top