Unsure what kind of hypothesis test to use

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SUMMARY

The discussion focuses on determining the appropriate hypothesis test for evaluating the effectiveness of a drug in preventing disease based on a clinical study involving 20 patients. The study design includes a treatment group receiving the drug and a control group receiving a placebo. The key findings indicate that if the drug is ineffective, the probability of contracting the disease can be modeled using a binomial distribution with parameters p=7/20 and n=10. Participants sought clarification on calculating the probability of 2 patients contracting the disease from the treatment group.

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das1
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The problem:

Researchers conduct a study to test the effectiveness of a drug preventing a disease. Of 20 patients in the study, 10 are randomly assigned to receive the drug and 10 to receive a placebo. After 1 year, suppose 5 patients in the control group contract the disease, while 2 patients who took the drug contract the disease.

For those who took the drug: 2 got the disease, 8 no disease.
For those who took placebo: 5 got the disease, 5 no disease.

If the drug is not effective, then every patient is equally likely to contract the disease. In that case, if 7 patients out of 20 contract the disease, what is the probability that 2 of them are in the treatment group? Also, what is the probability that 2 or fewer are in the treatment group?


So I don't know anything about the distribution, I also don't know what the probability of each patient getting the disease is. It almost seems like a binomial problem but I don't think I have enough info. If anyone can help me figure out how to approach this that would be much appreciated!
 
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das said:
The problem:

Researchers conduct a study to test the effectiveness of a drug preventing a disease. Of 20 patients in the study, 10 are randomly assigned to receive the drug and 10 to receive a placebo. After 1 year, suppose 5 patients in the control group contract the disease, while 2 patients who took the drug contract the disease.

For those who took the drug: 2 got the disease, 8 no disease.
For those who took placebo: 5 got the disease, 5 no disease.

If the drug is not effective, then every patient is equally likely to contract the disease. In that case, if 7 patients out of 20 contract the disease, what is the probability that 2 of them are in the treatment group? Also, what is the probability that 2 or fewer are in the treatment group?


So I don't know anything about the distribution, I also don't know what the probability of each patient getting the disease is. It almost seems like a binomial problem but I don't think I have enough info. If anyone can help me figure out how to approach this that would be much appreciated!

Hi das! (Wave)

That is exactly right.
Based on the evidence, the estimate that someone contracts a disease will be p=7/20, and the binomial distribution can then predict how many people out of n=10 will contract the disease.
What is the probability that 2 people will contract the disease?
 
Hi, thank you! That's what I suspected, I appreciate the affirmation
 

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