Uranium is by no mere coincidence considered a "transuranic element". The natural fusion process in a star stops at the point where iron is the end product, because there's nothing that you can do to make iron fuse. (It "refuses to fuse", it you'll pardon the term.) The only way for the process to proceed is through neutron-capture transmuting the iron into heavier elements, but even then they pretty much have to then break into smaller components which can then resume fusing.
I'm not expert in this area, but that's my general take on it.
(I'm deliberately ignoring the term "fissioning star" because that is self-contradictory and can't exist.)