Use Sauerbrey equation explain Δf Vs. analyte concentration

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Carmen Wong
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1. Explain, using the Sauerbrey equation, how the change in the resonance frequency of a quartz crystal can be related to an analyte concentration


2. Sauerbrey equation:
upload_2015-5-5_1-38-32.png



3. I knew Quartz crystal microbalance work according to the change of frequency after mass loaded, and when working in a Newtonian liquid the corresponding frequency shift is
upload_2015-5-5_1-42-29.png
(Kanazawa and Gordon, 1985), whichηL is the liquid viscosity; andμ is the shear modulus.
But I cannot understand the relation between the change of frequency and the analyte concentration according to the Sauerbrey equation.

thank you for helping
 
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Borek said:
And not through the adsorption isotherm?
Thank you for replying. It could be relate to the surface adsorption, but must explain according to the Sauerbrey equation.
 
I haven't said "don't use Sauerbrey equation". I said "combine it with an isotherm".
 
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