What Is the Correct Molarity of Glucose for Isotonic IV Solutions?

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SUMMARY

The correct molarity of glucose for isotonic intravenous (IV) solutions is approximately 0.303 M, which corresponds to an osmotic pressure of 7.7 atm at body temperature (35.9 Celsius). The equation used to determine this is P = MRT, where R is the ideal gas constant (0.0821 L atm K^−1 mol^−1) and T is the temperature in Kelvin (308.9 K). Discussions indicate that precision in significant figures and unit conversions, such as expressing the concentration in millimoles (mM), is crucial for accuracy in calculations.

PREREQUISITES
  • Understanding of osmotic pressure and its relation to molarity
  • Familiarity with the ideal gas law (P = MRT)
  • Knowledge of significant figures and unit conversions
  • Basic chemistry concepts related to solutions and concentrations
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  • Research the application of the ideal gas law in biological systems
  • Learn about the significance of isotonic solutions in medical applications
  • Explore the concept of osmolarity and its calculation
  • Study the importance of significant figures in scientific calculations
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Medical professionals, chemistry students, and anyone involved in preparing intravenous solutions will benefit from reading this discussion.

Torshi
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Human blood gives rise to an osmotic pressure of approximately 7.7 atm at body temperature, 35.9 Celsius.

What must the molarity of an intravenous glucose solution be to give rise to the same osmotic pressure as blood?

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I use the equation ; P=MRT if that's right
R is constant= .0821
T= 308.9 Kelvin
P=7.7 atm
M= ?

So would i rearrange the equation to P/RT=M
I get the wrong answer tho, and the answer doesn't sound right. I know I'm doing something wrong.
 
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What answer did you get, and how do you know it is wrong?

One thing: R is not 0.0821. It is 0.0821 L atm K^−1 mol^−1. Never let your numbers go out naked. Units are really, really important.
 
Torshi said:
bump
What answer did you get, and how do you know it's wrong?
 
pmsrw3 said:
What answer did you get, and how do you know it's wrong?

.303 M

and masteringchemistry says it's wrong...
 
Well, what you're doing looks right to me, and that answer is at least close to the correct concentration for isotonic glucose. All I can guess is that you need to have more or fewer sig figs, or maybe different units (e.g. 303 mM), or something like that.
 

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