What Is the Correct Molarity of Glucose for Isotonic IV Solutions?

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Discussion Overview

The discussion revolves around determining the correct molarity of a glucose solution that would create an osmotic pressure equivalent to that of human blood, which is approximately 7.7 atm at body temperature. The scope includes mathematical reasoning and potential corrections in the application of the ideal gas law in a biological context.

Discussion Character

  • Mathematical reasoning
  • Debate/contested

Main Points Raised

  • One participant states the osmotic pressure of blood is 7.7 atm and uses the equation P=MRT to find the molarity of glucose.
  • Another participant corrects the first by emphasizing the importance of units, specifically noting that R should be expressed with its units: 0.0821 L atm K^−1 mol^−1.
  • A participant shares their calculated answer of 0.303 M and mentions that it is deemed incorrect by a resource, MasteringChemistry.
  • Another participant suggests that the initial calculations appear correct and speculates that the discrepancy might be due to significant figures or unit conversions, such as expressing the concentration in millimoles per liter (mM).

Areas of Agreement / Disagreement

Participants do not reach a consensus on the correct molarity of glucose for isotonic solutions, and there are competing views regarding the accuracy of the calculations and the significance of unit conversions.

Contextual Notes

There are unresolved issues regarding the correct application of the ideal gas law, the significance of significant figures, and the appropriate units for expressing concentration.

Torshi
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Human blood gives rise to an osmotic pressure of approximately 7.7 atm at body temperature, 35.9 Celsius.

What must the molarity of an intravenous glucose solution be to give rise to the same osmotic pressure as blood?

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I use the equation ; P=MRT if that's right
R is constant= .0821
T= 308.9 Kelvin
P=7.7 atm
M= ?

So would i rearrange the equation to P/RT=M
I get the wrong answer tho, and the answer doesn't sound right. I know I'm doing something wrong.
 
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What answer did you get, and how do you know it is wrong?

One thing: R is not 0.0821. It is 0.0821 L atm K^−1 mol^−1. Never let your numbers go out naked. Units are really, really important.
 
Torshi said:
bump
What answer did you get, and how do you know it's wrong?
 
pmsrw3 said:
What answer did you get, and how do you know it's wrong?

.303 M

and masteringchemistry says it's wrong...
 
Well, what you're doing looks right to me, and that answer is at least close to the correct concentration for isotonic glucose. All I can guess is that you need to have more or fewer sig figs, or maybe different units (e.g. 303 mM), or something like that.
 

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