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What test or distribution should I use for before and after treatment?

Say, I have 30 subjects I test their blood before and after a pill they take a pill, what kind of test should I use?

I want to test mean difference, so, paired t-test? or Wilcoxon signed rank test?

The data looks like this

person before after

#1 100 89

#2 90 75

#3 120 100

#4 132 130

... ... ...

#30 141 120

I was told use binomial with normal approximation, but don't know why. I am so confused, how should I tell? someone please help. Thanks so much.

Say, I have 30 subjects I test their blood before and after a pill they take a pill, what kind of test should I use?

I want to test mean difference, so, paired t-test? or Wilcoxon signed rank test?

The data looks like this

person before after

#1 100 89

#2 90 75

#3 120 100

#4 132 130

... ... ...

#30 141 120

I was told use binomial with normal approximation, but don't know why. I am so confused, how should I tell? someone please help. Thanks so much.

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