Whether uracil was an amino acid or not

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Discussion Overview

The discussion revolves around the classification of uracil, specifically whether it is considered an amino acid. Participants explore its chemical nature and role in RNA compared to DNA, as well as implications for protein synthesis.

Discussion Character

  • Exploratory
  • Technical explanation
  • Debate/contested

Main Points Raised

  • One participant inquires about uracil's classification as an amino acid, referencing a previous discussion in an educational context.
  • Another participant asserts that uracil is a nitrogenous pyrimidine base found in RNA, not an amino acid, and notes its pairing with adenine in double-stranded RNA.
  • A different participant emphasizes that uracil contains nitrogen but lacks an amino group (NH2), reinforcing the point that it is not an amino acid.
  • One participant expresses curiosity about the functional differences between uracil and thymine, questioning the advantages of each in protein synthesis.
  • A later reply suggests that while uracil is not 'superior' to thymine, each has its advantages in different contexts, with thymine potentially providing more stability in DNA.
  • This participant speculates that uracil may have advantages in attracting anticodons during protein synthesis, though they acknowledge uncertainty and invite further clarification from knowledgeable members.

Areas of Agreement / Disagreement

Participants generally agree that uracil is not an amino acid and is a component of RNA. However, there is ongoing debate regarding the functional differences and advantages of uracil versus thymine in biological processes.

Contextual Notes

Some claims about the roles of uracil and thymine in protein synthesis and stability are presented with uncertainty, and the discussion includes speculative reasoning without definitive conclusions.

jimmy p
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I while back (in the distant days when i was in education...I'm a day out of education now!) we were studying amino acids in chemistry, and I asked my chemistry teacher whether uracil was an amino acid or not. She didnt know but said she would find out, which she didnt, so I am asking the experts now!

"Is uracil an amino acid?" :approve:
 
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No uracil is a nitrogenous pyrimidine base found in RNA but not DNA. In double-stranded RNA it pairs with adenine. In DNA, uracil is replaced by thymine.
 
Uracil is a base found in RNA and is derived from pyrimidine, it contains nitrogen but no amino group (NH2) so it's not an amino acid.
 
YEH! I wanted to answer :-p
 
You snooze you lose :biggrin:
 
So it is a fake? what a clever thing protein synthesis is. That doesn't really make much sense though, what is the point in thymine? Why is uracil better?
 
jimmy p said:
So it is a fake? what a clever thing protein synthesis is. That doesn't really make much sense though, what is the point in thymine? Why is uracil better?

Uracil isn't 'superior' to Thymine on a whole, but each have their advantages in each situation.
Thymine is present in DNA - the encoded information for synthesis of proteins, while it is replaced by uracil in mRNA/tRNA/rRNA.
While I'm not sure of the reason for it i would expect thymine possibly holds the DNA together in a more stable manner (as it is storage) and uracil holds some advantage in attracting the anticodons carrying amino acids to the ribosomes. Perhaps uracil exhibits a greater electronegativity?
Who knows.., that's merely my uninformed ramblings, perhaps the mentors can clear this up.
 

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