Why Are Pulmonary Alveoli and Kidney Nephrons Spherical Instead of Tetrahedral?

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SUMMARY

Pulmonary alveoli and kidney nephrons are spherical structures optimized for maximizing surface area relative to volume, crucial for their functions in gas exchange and filtration. Despite the tetrahedron being the ideal shape for surface area-to-volume ratio (7.21), spheres are utilized due to their ability to equalize surface tension, particularly in the alveoli, where surface tension is a significant factor. The spherical shape accommodates the dynamic changes in size during breathing, enhancing functionality. This design reflects a biological compromise balancing multiple factors beyond mere surface area efficiency.

PREREQUISITES
  • Understanding of pulmonary physiology and gas exchange mechanisms
  • Knowledge of renal physiology and nephron function
  • Familiarity with surface area-to-volume ratio concepts
  • Basic principles of fluid dynamics and surface tension
NEXT STEPS
  • Research the role of surface tension in pulmonary alveoli function
  • Explore the structural adaptations of kidney nephrons for filtration efficiency
  • Investigate the implications of shape on biological structures in other organs
  • Study the principles of fluid dynamics as they relate to biological systems
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Biologists, medical students, physiologists, and anyone interested in the structural adaptations of organs for optimal function in gas exchange and filtration processes.

edwardone123
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In a human body we have two relatively similar structures -pulmonary alveoli(https://www.google.com/url?sa=i&sou...aw1ZCQJEi4eFj0awKq5CtTeT&ust=1555210875346706)
and kidney nephrone capsule
(https://qph.fs.quoracdn.net/main-qimg-0633a201014408ed330c31420225e4e6.webp)

Both of these organelles has similar function- provide maximal exposure (max volume of processed air/blood ) for given volume.
In lungs we would expect,that alveoli would give max amount of air to blood surrounding alveoli ,in kidneys -that capusle of nephrone would expose max amount of primary urine to contact with blood behind some barriers.
In both cases it would be logical to think that we need shape of these organelles to have max surface to volume ratio .
According to (https://en.wikipedia.org/wiki/Surface-area-to-volume_ratio ) the ideal shape for this task would be tetrahedron(A/v ratio -7.21)
In reality we have sphere -capsule with ratios 5.25-4.8
Why Mother Nature would not change it shape ?
Do you see any benefits in spherical shape ?
Please do not mention turbulence as an argument for spherical/capsule shape
Thank you
 
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Often selection will drive biology to a compromise position to balance several different factors.
In the case of the alveoli, factors other than packing that may be involved:
Surface tension in the alveoli is strong enough in the small alveoli to be important and is regulated to maintain it properly. Spheres will equalize the tension over the surface of the alveoli, a shape with flat sides and angular edges would have an uneven distribution of tension over its surface. I expect that they would tend to equalize on the very small scale involved to forma sphere. I expect that this would be a major factor. Alveoli change size during breathing. This may work better with a spherical shape.
 
also interesting :
 
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