Why Do Some Why Questions in Biology Remain Unanswered?

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Discussion Overview

The discussion centers around the challenges of answering "why" questions in biology, particularly in relation to evolutionary advantages and the physiological mechanisms of behavior. Participants explore the distinction between proximate and ultimate causes, the limitations of current knowledge, and the philosophical implications of certain questions.

Discussion Character

  • Exploratory
  • Conceptual clarification
  • Debate/contested

Main Points Raised

  • Some participants express frustration that "why" questions often receive evolutionary explanations rather than specific physiological mechanisms related to brain function.
  • Others clarify that while we know much about brain functions, significant gaps in understanding remain, making it difficult to address the original question fully.
  • A distinction is made between proximate causes (physiological mechanisms) and ultimate causes (evolutionary reasons) in biology, with both being poorly understood for complex traits.
  • One participant argues that identifying brain regions involved in behavior does not significantly enhance predictive power regarding human behavior, as the connection between neurons and conscious decisions is still unclear.
  • Concerns are raised about the limitations of evolutionary explanations, particularly at the individual level, where variation and selection against certain traits complicate understanding.
  • Some questions are suggested to be more philosophical than scientific, with examples given that challenge the ability of science to provide definitive answers to certain "why" questions.

Areas of Agreement / Disagreement

Participants generally agree that there are significant challenges in answering "why" questions in biology, particularly regarding the distinction between proximate and ultimate causes. However, there is no consensus on the adequacy of current explanations or the nature of certain questions, with some viewing them as philosophical rather than scientific.

Contextual Notes

Limitations include the incomplete understanding of complex traits and behaviors, the dependence on definitions of proximate and ultimate causes, and the unresolved nature of certain philosophical questions related to biological phenomena.

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The "why" questions in biology

Usually when I ask "why" questions in biology I get answers like - because it was advantageous on an evolutionary point of view.
But why don't I get answers like - because so-and-so part of the brain acts in so-and-so way.
Don't we have enough knowledge to really know which part of the brain does what yet?
 
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We need a little more information to address your question. We know a lot about which part of the brain relates to this or that function, be it visual processing, appetite, hearing, movement, and so on. There's also a lot, of course, we don't know about the brain. And, yes, the evolutionary advantages of various brain and body features are a good way to infer "why" some body feature exists in some animals. Soooo, I'm not sure what your question is. Perhaps you can elaborate.
 
For "why" questions in biology, we usually consider answers on one of two scales: proximate causes and ultimate causes. This distinction was originally proposed by Ernst Mayr in his classic paper, Cause and Effect in Biology.

The ultimate causes in biology relate to answering why a certain trait or behavior evolved. However, in the case you cite, the proximate causes – those relating to the physiological mechanism for a trait or behavior – are the ones you want to know.

It's important to note that for most complex traits and behaviors, both the proximate and ultimate causes are not well understood and are areas of active research. As DiracPool said, it's hard to say something more than that in response to your question without knowing more details about the questions you're asking.
 
In addition to what everyone else said, it is not that much better of an explanation to say what parts of the brain are involved in some behavior than to just say the brain does it, in the sense that it adds little to the ability to make predictions about human behavior, or to understand how different behaviors are connected.

If you asked how a person found his way home, it does not take much away from the mystery of it to say that the hippocampus is involved, compared to saying the brain is involved. It would be useful to know that in order to predict the effect of brain damage, for example, and it is probably an important clue to looking for a more specific explanation, but by itself, it doesn't add much. The way that conscious human decisions emerge from neurons is not well understood in anything like the level of detail needed to answer why a particular person made a particular decision at the level of neurons, or even why people on average are more likely to make one conscious decision than another.

Evolutionary explanations are somewhat easier to come up with, but in the absence of detailed knowledge about how particular genes manifest themselves in particular behaviors through environmental interaction, there is always in principle the possibility that a behavior is a side effect of some gene selected for another reason. Also, evolutionary explanations only really work at the population level. On the individual level, there is always variation, and some of it is always being actively selected against, so evolution will never explain it.
 
In addition there are certain "why" questions that are more in the realm of Philosophy than Science. Many questions can be broken down to more and more basic Sciences but you get to a point where you ask something like, "Why is the genetic material DNA/RNA and not XXX?" Some people may come up with certain reasons based on some Physical arguments (like Physical/Chemical properties etc) but its pretty much a Philosophical question akin to asking why is the speed of light 3e8 m/s?

You have to remember that Science deals with Physical realities. Abstractions are used as tools to explain/model things but we cannot always answer all why-type questions with Science.
 

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