If microorganisms are present, then the water should become turbid as they multiply. However, this is not necessarily the case. Fertilization is done on a regular basis, daily or 2-3x a week.
The nutrients are NPK and maybe micros (which include Fe, Mg, Mn, B, Cu, Zn, and Mo.)
UV sterilizers should remove any free floating organisms, as well as deactivate certain chelated nutrients such as Fe chelate, if added to the water column.
I should add that fish keepers have found that the more frequent the water changes, the faster they grow and the healthier the fish. This is why many fish farms do daily 100% water changes. The reason why, according to this article, may be the result of nanobubbles, though nanobubbles are purposefully added to the water.
Oxygen and Air Nanobubble Water Solution Promote the Growth of Plants, Fishes, and Mice
http://www.plosone.org/article/info:doi/10.1371/journal.pone.0065339
Whether or not nanobubbles are present in tap water and/or reverse osmosis water is yet to be determined, which is why I asked in the physics forum about the formation of nanobubbles.