It would be easier to respond with a concrete example. What is a question about magnitude that meets all of the following criteria?
1) The answer is dependent on units.
2) The question is not, even on on closer examination, better framed as a question about the ratio of two magnitudes (so that the units cancel).
3) The question meets your standard for being "not ... a meaningless question".
I submit that any such question will turn out to be about how we're defining our units, not about how the universe works.