Absorbed dose: organ dose manual calculation

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Absorbed dose , organ dose manual calculation
Dear Experts . How can I calculate the absorbed dose for any organ with mathematical formulas? For example, radio nuclide Ra -223 ,organ liver, time 1 hour , activity 1MBq.What methods can I use? Is there a pdf or book about it?
 
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You can start here with The Committee on Medical Internal Radiation Dose (MIRD)

Committee on Medical Internal Radiation Dose (MIRD)

Radiation dosimetry provides the fundamental quantities used for radiation protection, risk assessment, and treatment planning. The MIRD Committee develops standard methods, models, assumptions, and mathematical schema for assessing internal radiation doses from administered radiopharmaceuticals. The MIRD approach simplifies the problem of assessing dose for many different radionuclides—each with its unique radiological characteristics and chemical properties as labeled compounds—in the highly diverse biological environment represented by the human body, internal organs, tissues, fluid compartments, and cells. The virtue of the MIRD approach is that it systematically reduces complex dosimetric analyses to methods that are relatively simple to use, including software tools for experimental and clinical use.

http://www.snmmi.org/AboutSNMMI/CommitteeContent.aspx?ItemNumber=12475&navItemNumber=763
 
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