Adapting the Donnan Equation for 3 Diffusible Ions

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SUMMARY

The discussion focuses on adapting the Donnan Equation for three diffusible ions, specifically addressing the challenges of incorporating the Goldman Equation without having the relative permeabilities. Participants emphasize the necessity of understanding the ionic concentrations and their respective permeabilities to accurately apply the equations. The conversation highlights the limitations faced when attempting to solve for chloride ions under these conditions.

PREREQUISITES
  • Understanding of the Donnan Equation
  • Familiarity with the Goldman Equation
  • Knowledge of ionic concentrations and permeabilities
  • Basic principles of electrochemical gradients
NEXT STEPS
  • Research the application of the Goldman Equation in multi-ion systems
  • Study methods for determining relative permeabilities of ions
  • Explore advanced topics in electrochemical gradients
  • Investigate case studies involving the Donnan and Goldman Equations
USEFUL FOR

Researchers in biophysics, students studying membrane transport, and professionals working with ion channels and electrochemical systems will benefit from this discussion.

garytse86
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How do you adapt the Donnan Equation to 3 difffusible ions?
 
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Use the Goldman Equation?
 
I don't have the relative permeabilities.
 
here is the Q, can't do the chloride part.
 

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