Ambiguous gene/protein nomenclature

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SUMMARY

The discussion centers on the confusion surrounding gene and protein nomenclature, specifically the CREBBP gene and its associated protein, CRB. Participants emphasize the importance of using official gene symbols consistently, as discrepancies can arise when proteins are referred to by different names, such as CBP for CREBBP. The consensus is that the gene encodes a single protein, and clarity in nomenclature is crucial for accurate scientific communication.

PREREQUISITES
  • Understanding of gene and protein nomenclature conventions
  • Familiarity with the CREBBP gene and its functions
  • Knowledge of protein naming systems in molecular biology
  • Awareness of common alternative names for proteins, such as CBP
NEXT STEPS
  • Research the official nomenclature guidelines from the Human Genome Organisation (HUGO)
  • Explore the implications of gene/protein name discrepancies in scientific literature
  • Learn about the role of the CREBBP gene in cellular processes
  • Investigate the naming conventions for other genes and their proteins to identify common patterns
USEFUL FOR

Researchers, molecular biologists, and geneticists who are involved in gene/protein studies and require clarity in nomenclature for accurate data interpretation and communication.

Monique
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I'm writing a paper and run into the issue that co-authors claim that certain genes have different names as a protein :confused:

Like the CREBBP gene, encodes CRB protein?

As far as I know the gene encodes for a single protein, who in the right mind would give it a different name? I'm for using the official gene symbol, also for the protein. Anyone has had a similar encounter?
 
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crb seems to be used for genes called "crumbs"

I have seen CBP as an alternative to CREBBP... maybe that's what they/you meant?
 
Pythagorean said:
I have seen CBP as an alternative to CREBBP... maybe that's what they/you meant?
Not an alternative, the suggestion is that the protein has a different official symbol than the gene.
 

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