An open access review of the Asgard Archaea

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SUMMARY

The Asgard archaea are widely accepted as the microbial ancestors that fused with alphaproteobacteria to form eukaryotic cells, including animals, plants, and fungi. This review comprehensively addresses molecular, metabolic, and structural characteristics of Asgard archaea. Experimental approaches involving a modified Miller-Urey setup combined with strains of Asgard archaea and alphaproteobacteria or cyanobacteria aim to induce endosymbiosis in laboratory conditions. Culturing Asgard archaea is challenging due to their slow division rates and requires specialized techniques practiced by only a few laboratories.

PREREQUISITES

  • Asgard archaea molecular biology and metabolism
  • Endosymbiosis theory and mechanisms
  • Modified Miller-Urey experimental setup
  • Microbial culturing techniques for slow-dividing archaea

NEXT STEPS

  • Research specialized culturing methods for Asgard archaea
  • Study alphaproteobacteria and cyanobacteria interactions in endosymbiosis
  • Explore laboratory protocols for modified Miller-Urey experiments
  • Investigate molecular markers for detecting induced endosymbiosis

USEFUL FOR

Microbiologists, evolutionary biologists, molecular biologists, and researchers studying the origin of eukaryotes and experimental endosymbiosis techniques.

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Asgard archaea: have we found our microbial ancestors?

The Ascard Archaea are now widely hypothesized to have fused with alphaproteobacteria (that became mitochondria) to form the eukaryotes (cells with nuclei and lots of internal membrane systems that form animals, plants and fungi).
This review covers a lot of molecular, metabolic, and structural issues.
 
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It's really interesting to read more about this because I had a similar hypothesis a few years back. As I head into Uni I plan on seeing if I can get a professor to sponsor me so I can use a modified Miller-Urey setup alongside different strains of Asgard Archaea and either alphaproteobacteria or cyanobacteria to attempt induced-endosymbiosis in a laboratory setting.
 
emitted_echo said:
It's really interesting to read more about this because I had a similar hypothesis a few years back. As I head into Uni I plan on seeing if I can get a professor to sponsor me so I can use a modified Miller-Urey setup alongside different strains of Asgard Archaea and either alphaproteobacteria or cyanobacteria to attempt induced-endosymbiosis in a laboratory setting.
Any experiment involving these Asgard guys would take a long time since they divide very slowly. There are probably special culturing techniques only a few labs would be doing regularly. It would be best to go to a lab that is already doing this.
 

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