Antibiotic effects of salvia apiana

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SUMMARY

Salvia apiana has demonstrated the ability to completely inhibit the growth of four test organisms, as noted in a study referenced in the discussion. The compound 16-hydroxy-12-methoxy-methylcarnosate appears to be the most promising for potential medicinal use, although its properties remain largely unexplored. The discussion raises questions about the efficacy of smoking or nebulizing antibiotics as a method of delivery, suggesting that inhalation could be superior to oral administration due to reduced gastrointestinal impact. The conversation also touches on historical uses of inhaled substances for medical purposes, highlighting a gap in modern practices.

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  • Understanding of phytochemistry and plant compounds
  • Knowledge of antibiotic mechanisms and testing methods
  • Familiarity with routes of administration (ROA) for drug delivery
  • Basic principles of pharmacology and inhalation therapy
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  • Research the pharmacological properties of 16-hydroxy-12-methoxy-methylcarnosate
  • Investigate the historical use of inhaled medications and their efficacy
  • Explore the development of nebulized antibiotics and their clinical applications
  • Study the effects of different routes of administration on drug absorption and efficacy
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Researchers in pharmacology, herbal medicine enthusiasts, healthcare professionals exploring alternative antibiotic delivery methods, and individuals interested in the medicinal properties of Salvia apiana.

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I found this article:
http://arizona.openrepository.com/arizona/handle/10150/185511
Heres a quote from it:
Salvia apiana was the only plant in this study to completely inhibit the growth of all four test organisms
I recently (before I came across that article) tried smoking this herb to satisfy a spontaneous urge so this gets me wondering if smoking this substance could be used to combat lung and nasal infections. I'm not suggesting anyone try this as that would be reckless and dangerous because the plant may contain harmful compounds and burning them may produce additional harmful degradents but I think its worth researching. They isolated numerous compounds from this species of salvia but the most promising one seems to be 16-hydroxy-12-methoxy-methylcarnosate. I can't find any info on this compound but I suppose we could make an educated guess on what the boiling point and decomposition point of the compound may be. I'm a chem major but I'm in no way experienced enough to make a good estimate on something like that. Any takers?

EDIT: Also, why are there not more smoked or nebulised antibiotics in use? I'd assume intravenous or inhalation would be a superior route for many infections because you avoid wiping out your gastrointestinal fauna of friendly bacteria like you do when taking them orally. I'm guessing its down to convenience. More convenient for a person to pop a pill than inject themselves. Inhalers are pretty convenient though. I've never heard of smoking being used in conventional medicine, I wonder why. Inhaling the vapour of a volatile drug compound is an effective ROA.
 
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Ah, I completely forgot about asthma cigarettes. My father told me that when he was a kid, asthmatic kids would bring datura (a plant containing atropine and other anticholinergics) into school and use them recreationally to induce a state of delerium. I suspect they are a thing of the past for obvious reasons.
 
You post some weird topics. Anyways, why do you need smoke everything. Why isn't eating it or boiling it and drink it like any better of a solution like all herbs that were used thousands of years ago ? Are you smoking it to get high or something.
 
Why not smoke it? Inhaling vapour allows the substance to be rapidly absorbed through the lungs and then carried, via the pulmonary vein to the heart, which pumps it throughout the body. Its a vastly superior ROA to oral ingestion. Cheaper than going out and buying a nebuliser. No, I did smoke salvia apiana to get high. As far as I know, there are no psychoactive compounds present in it. Salvia officianalis on the other hand contains thujone but I wouldn't particularly consider ingesting a GABA_a antagonist and 5-HT3 antagonist enjoyable.

BTW who says I smoke everything? I don't even smoke tobacco. I take the occasional bong hit of datura and belladonna every now and then but that's it. Only joking, only the profoundly deranged would ingest anticholinergics recreationally.
 

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