Are Leading and Lagging Strands Parent or Daughter DNA?

  • Thread starter Thread starter hivesaeed4
  • Start date Start date
Click For Summary

Discussion Overview

The discussion revolves around the classification of leading and lagging DNA strands in the context of DNA replication, specifically whether these strands are considered parent or daughter strands. The scope includes conceptual clarification of terminology used in molecular biology.

Discussion Character

  • Conceptual clarification, Debate/contested

Main Points Raised

  • One participant expresses confusion about whether leading and lagging strands are original (parent) or newly synthesized (daughter) strands.
  • Another participant suggests that leading and lagging strands are usually referred to as daughter strands, but notes that terminology is not fixed.
  • A third participant elaborates that the terms "leading" and "lagging" refer to daughter strands, as the parent strand can serve as a template for both types of synthesis.

Areas of Agreement / Disagreement

There is no clear consensus on the terminology, as participants acknowledge variability in how the terms are used. Some participants assert that leading and lagging strands are daughter strands, while others note the flexibility in terminology.

Contextual Notes

The discussion highlights the potential for ambiguity in the definitions of leading and lagging strands, depending on the context in which they are used.

hivesaeed4
Messages
217
Reaction score
0
I'm confused regarding one aspect concerning the leading and the lagging strands. Are they the strands which were present before replication occurs (i.e. the original/parent strands) or are they the strands which come into being after replication is completed (i.e. the newly synthesized/daughter strands).

Note:- I understand the 5' to 3' and vice versa distinctions/definitions of the two so don't explain in terms of that.
 
Biology news on Phys.org
Usually the daughter strands (but the terminology is not so fixed that you can't say "leading strand replication" or "leading parent strand" or "leading template strand").

http://www.ncbi.nlm.nih.gov/books/NBK26850/ (Fig. 5.8)
http://www.ncbi.nlm.nih.gov/books/NBK21751/ (Fig. 12.9)
 
As atyy said, "leading" and "lagging" refer to the daughter strands. This is in part because the parent strand can template both leading and lagging strand synthesis. For example, consider a replication bubble. On the side of the bubble, the left side of the bubble, the top parent strand acts as the template for leading strand synthesis while on the right, the same parent strand acts as the template for lagging strand synthesis.
 
That cleared up any confusion I had. Thanks.
 

Similar threads

Replies
2
Views
5K
  • · Replies 2 ·
Replies
2
Views
4K
  • · Replies 3 ·
Replies
3
Views
67K
  • · Replies 6 ·
Replies
6
Views
11K
  • · Replies 4 ·
Replies
4
Views
3K
  • · Replies 4 ·
Replies
4
Views
14K
  • · Replies 5 ·
Replies
5
Views
2K
  • · Replies 4 ·
Replies
4
Views
2K
  • · Replies 64 ·
3
Replies
64
Views
2K
  • · Replies 100 ·
4
Replies
100
Views
10K