Aspirin/Ibprofen Solubility in Water vs Benzoic Acid

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SUMMARY

Aspirin and Ibuprofen exhibit lower solubility in water compared to Benzoic Acid due to their molecular structures and the presence of non-polar hydrocarbon groups. The polarity of the functional groups significantly influences solubility; compounds with more polar functional groups tend to dissolve better in water. The discussion emphasizes the importance of analyzing molecular structures to predict solubility behavior in aqueous environments.

PREREQUISITES
  • Understanding of molecular polarity and its effects on solubility
  • Familiarity with chemical structures of Aspirin, Ibuprofen, and Benzoic Acid
  • Basic knowledge of organic chemistry principles
  • Concept of hydrophobic and hydrophilic interactions
NEXT STEPS
  • Research the solubility principles of organic compounds in water
  • Study the molecular structures of Aspirin, Ibuprofen, and Benzoic Acid in detail
  • Learn about the impact of functional groups on solubility
  • Explore the concept of hydrophobic interactions in organic chemistry
USEFUL FOR

Chemistry students, organic chemists, and anyone interested in the solubility properties of pharmaceutical compounds.

Ryan_77
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Would you expect to that Aspirin and Ibprofen are more or less soluble in water than benzoic acid? ( I believe it has something to do with the polarity of the bonds but I am unsure how to choose between the two.)
 
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Look at the structures. If you put a bunch of greasy groups on the aromatic group what will happen to solubility in water?
 

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