Bacteria make major evolutionary shift in the lab

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Discussion Overview

The discussion centers around a recent article detailing a significant evolutionary shift observed in bacteria, specifically focusing on the E. coli long-term evolution experiment conducted by Richard Lenski. Participants explore the implications of this evolutionary change, the nature of the traits developed, and the experimental validation of such findings.

Discussion Character

  • Exploratory
  • Debate/contested
  • Technical explanation

Main Points Raised

  • Some participants highlight the unprecedented nature of the evolutionary innovation observed, particularly the ability of E. coli to metabolize citrate, which is typically not utilized by this bacterium.
  • Questions arise regarding the necessity of replicating the phenomenon to validate the experiment's findings, with some arguing that without replication, the results cannot be considered conclusive.
  • Others draw comparisons between this evolutionary change and the common occurrence of bacteria developing drug resistance, suggesting that both represent forms of evolutionary adaptation.
  • A participant notes that the emergence of beneficial traits in this context differs from drug resistance, which often arises from mutations that are not advantageous in non-antibiotic environments.
  • Some participants mention that a subset of the bacterial populations evolved a higher mutation rate, which may have conferred a selective advantage.
  • There is a suggestion that the experiments are not new, with one participant indicating that the foundational observations occurred many generations prior to the citrate-utilizing trait's emergence.
  • One participant asserts that evolution does not follow a linear path, implying that the experimental outcomes do not need to be replicated to support the concept of evolutionary change.

Areas of Agreement / Disagreement

Participants express differing views on the implications of the findings, the necessity of replication for validation, and the nature of evolutionary processes. No consensus is reached regarding the interpretation of the results or their significance.

Contextual Notes

Some discussions reference the complexity of evolutionary processes and the conditions under which traits may be beneficial or detrimental, indicating that the interpretations of the findings depend on specific assumptions and definitions.

daniel_i_l
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I recently came across this article:
http://www.newscientist.com/article/dn14094-bacteria-make-major-evolutionary-shift-in-the-lab.html
A major evolutionary innovation has unfurled right in front of researchers' eyes. It's the first time evolution has been caught in the act of making such a rare and complex new trait.

And because the species in question is a bacterium, scientists have been able to replay history to show how this evolutionary novelty grew from the accumulation of unpredictable, chance events.
...

Mostly, the patterns Lenski saw were similar in each separate population. All 12 evolved larger cells, for example, as well as faster growth rates on the glucose they were fed, and lower peak population densities.

But sometime around the 31,500th generation, something dramatic happened in just one of the populations - the bacteria suddenly acquired the ability to metabolise citrate, a second nutrient in their culture medium that E. coli normally cannot use.
Has anything on this scale ever been observed before?
Lenski's freezer must be an immensely valuable source of evolutionary information.
And one question, why is "lower peak population densities" something E. coli would evolve towards. Wouldn't the more successful ones have a higher population density?
 
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Wouldn't they have to recreate the phenomenon before they could say the experiment "proves" anything?

On the other hand, is this different than a bacteria/virus gaining a resistance to a drug? Isn't that a commonly occurring form of evolution along the same lines?
 
Pattonias said:
Wouldn't they have to recreate the phenomenon before they could say the experiment "proves" anything?

On the other hand, is this different than a bacteria/virus gaining a resistance to a drug? Isn't that a commonly occurring form of evolution along the same lines?

Not really.

Most of the immune-resistency comes out of normally "failed" bacteria, i.e, where that structure the anti-biotic targets works IMPROPERLY (thus, the anti-biotic fails to hook onto that defective structure).

I.e, these mutants would in a non-anti-biotic setting have lower reproduction rates etc than the standard strand, and be quickly swamped/smothered.


In this case, however, a strictly beneficial trait is seen to emerge, rather than a trait which is onnly beneficial in a much more specialized setting (i.e, the anti-biotic environment)
 
I think these experiments are old...
 
Sorry! said:
I think these experiments are old...

Well, if they have established that gen 20.000 could give rise to citrate-utilizing gen 32.000, then clearly, the initial observation of citrate-utilization happened well over 10.000 generations ago.
 
Pattonias said:
Wouldn't they have to recreate the phenomenon before they could say the experiment "proves" anything?
No: evolution does not claim to be a linear process.
 

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