This discussion focuses on enzyme inhibitors in the human body, specifically identifying examples of competitive reversible inhibitors, non-competitive reversible inhibitors, and irreversible inhibitors. Competitive reversible inhibitors, such as statins and methotrexate, compete with substrates for active sites on enzymes. Non-competitive reversible inhibitors include lithium and some heavy metals, which bind to enzymes regardless of substrate presence. Irreversible inhibitors, such as aspirin and penicillin, permanently deactivate enzymes by forming covalent bonds.
PREREQUISITESStudents in biochemistry, healthcare professionals, and researchers interested in enzyme function and pharmacology.