Can viruses be stored in a box without decaying?

  • Thread starter Thread starter SIQI
  • Start date Start date
  • Tags Tags
    Box
Click For Summary

Discussion Overview

The discussion revolves around the feasibility of storing viruses in a box without decay, exploring the conditions necessary for their preservation and functionality. Participants examine theoretical and practical aspects of virus storage, including environmental factors and suitable mediums.

Discussion Character

  • Exploratory
  • Technical explanation
  • Debate/contested

Main Points Raised

  • Some participants propose that viruses can be stored in a container isolated from electromagnetic waves and other forces, suggesting that they could function normally upon reintroduction to a host.
  • Others argue against this analogy, stating that viruses require a specific environment, such as an aqueous medium, to maintain their structural integrity and functionality, and that drying out can lead to irreversible damage.
  • One participant shares personal experience with suspending viruses in polyethylene glycol (P.E.G.), claiming that this method effectively preserves their functionality even after freezing and thawing, and emphasizes the importance of the storage medium over external forces.
  • Visual evidence is presented, comparing the effects of different storage conditions on viral samples, highlighting the differences in preservation outcomes.

Areas of Agreement / Disagreement

Participants do not reach a consensus; there are competing views on the viability of storing viruses in isolation versus the necessity of a suitable medium for preservation.

Contextual Notes

Limitations include the lack of detailed scientific evidence supporting the claims made about virus storage and the potential variability in virus types and their specific storage requirements.

SIQI
Messages
6
Reaction score
0
I see no reason why it can't be done, can't find any information on it in google. I think of a virus like a lego piece, it does what it does due to its shape and material. I couldn't find anything in regards to a virus's self decay.

If you shelve it in a container that isolates it away from EM waves so there is no other force outsides of gravity affecting its state of being, can it not function all the same once the container is reopened and the virus some how is introduced and bypasses the host's defenses?
 
Biology news on Phys.org
SIQI said:
I see no reason why it can't be done, can't find any information on it in google. I think of a virus like a lego piece, it does what it does due to its shape and material. I couldn't find anything in regards to a virus's self decay.

If you shelve it in a container that isolates it away from EM waves so there is no other force outsides of gravity affecting its state of being, can it not function all the same once the container is reopened and the virus some how is introduced and bypasses the host's defenses?
Whatcha' got in mind there, Scooter?
 
A virus is not a lego brick. For example, components of viruses exist in an aqueous environment and, like all proteins, depend on being surrounded by water in order to properly fold into the correct shape. If the virus dries out, its components will no longer function, and in many cases, this loss of function is irreversible. Existing in a watery environment also poses some challenges as water can chemically react with components of the virus, breaking them apart, though this would occur at a much slower rate than dehydration of the virus under normal conditions.
 
  • Like
Likes   Reactions: russ_watters, jim mcnamara and Ryan_m_b
Yes, if you want to store a "Live" virus and want it not to decay, the best thing to suspend the virus in so it will not decay is polyethylene gycol 300 or 400 or P.E.G.. I have suspended many viruses in this liquid and 99% of the time they reactivate upon release from this substance despite that time passed even after freezing and thawing in aqueous P.E.G.. It is not about the forces of nature damaging them more about protein damage by other organisms or chemicals or lack of proper storage medium that make them nonfunctional. I have several stored in test tubes filled with viruses or Viral Vectors and this aqueous P.E.G., it isn't a box but close, a sealed test tube.

cas-no-25322-68-3-Poly-ethylene.jpg_350x350.jpg


Virus or Viral Vector Suspended in aqueous P.E.G.

JgUUpIw.png


If you want to see something even more interesting look at this, set of tubes.

The Left one is one not suspended in aqueous P.E.G. making "Viral plaques" on the inside of the tube, The middle one is aqueous P.E.G. the clear liquid storage medium, The Right a Virus or Viral Vector Suspended in aqueous P.E.G.

keYl83b.jpg


In any case, there is your answer from someone who has done this.

P.S. : Sorry, for the poor lighting.
 

Attachments

  • cas-no-25322-68-3-Poly-ethylene.jpg_350x350.jpg
    cas-no-25322-68-3-Poly-ethylene.jpg_350x350.jpg
    15.8 KB · Views: 606
  • JgUUpIw.png
    JgUUpIw.png
    37.6 KB · Views: 515
  • keYl83b.jpg
    keYl83b.jpg
    4.6 KB · Views: 585
Last edited:
  • Like
Likes   Reactions: BillTre

Similar threads

Replies
1
Views
3K
  • · Replies 9 ·
Replies
9
Views
14K
  • · Replies 14 ·
Replies
14
Views
3K
  • · Replies 14 ·
Replies
14
Views
17K
  • · Replies 12 ·
Replies
12
Views
18K
  • · Replies 35 ·
2
Replies
35
Views
2K
  • · Replies 10 ·
Replies
10
Views
5K
  • · Replies 16 ·
Replies
16
Views
7K
  • · Replies 34 ·
2
Replies
34
Views
5K
  • · Replies 1 ·
Replies
1
Views
3K