Cardiovascular system and Nitric-Oxide

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SUMMARY

Nitric oxide (NO) is a crucial endothelial-derived vasodilator that plays a significant role in the cardiovascular system by signaling smooth muscle relaxation, thereby enhancing blood flow. It is biosynthesized from arginine and oxygen through nitric oxide synthase (NOS) enzymes and can also be produced by the reduction of inorganic nitrate. Inhalation of NO is applicable in specific medical circumstances, particularly during surgeries. Ongoing research continues to explore its benefits and applications in cardiovascular health.

PREREQUISITES
  • Understanding of nitric oxide synthase (NOS) enzymes
  • Knowledge of vasodilation mechanisms
  • Familiarity with the biochemical synthesis of nitric oxide from arginine
  • Awareness of the role of endothelial cells in cardiovascular function
NEXT STEPS
  • Research the latest studies on nitric oxide's role in cardiovascular diseases
  • Explore the therapeutic applications of inhaled nitric oxide in clinical settings
  • Investigate the biochemical pathways of nitric oxide synthesis and its regulation
  • Learn about the effects of inorganic nitrate on nitric oxide production
USEFUL FOR

Medical researchers, cardiovascular specialists, and healthcare professionals interested in the therapeutic applications of nitric oxide in cardiovascular health.

djflush
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I would like to start a disscusion on the benefits of NO and its function in the cardiovascular system.If anyone can recommend research papers/citations for study this would be great. Some basic fundamentals about this chemical are that it is a endotheium derived vasodiator.It is a signalling molecule biosynthesised endogenously from arginine and oxygen by various nitric oxide synthase (NOS) enzymes and by reduction of inorganic nitrate. The endothelium of blood vessels use nitric oxide to signal the surrounding smooth muscle to relax, thus resulting in vasodilation and increasing blood flow.
I think it may be inhaled under certain circumstances and surgeries.
My objective is to find out more about it and some ongoing research projects.
 
Biology news on Phys.org
NO is http://anesthesiology.pubs.asahq.org/article.aspx?articleid=1931823.
 

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