1. Limited time only! Sign up for a free 30min personal tutor trial with Chegg Tutors
    Dismiss Notice
Dismiss Notice
Join Physics Forums Today!
The friendliest, high quality science and math community on the planet! Everyone who loves science is here!

Chi square Dominant phenotype problem

  1. Feb 26, 2010 #1
    What is the ChiSquare value for the dominant phentotype of the cross Purple versus White. Shouldn't the answer be 696 or 696.75??



    Parental Phenotypes

    Purple X White


    F1 Phenotype

    All Purple


    F2 Phenotype

    705 purple, 224 white


    I must be missing something:

    Observed Purple=705

    Observed White= 224

    Total 929

    Expected for Purple 705/929=.75

    .75x929= 696.75 Purple Expected

    Expected White 224/929=.24

    .24 x 929= 222.96 White Expected



    Second part of the question is

    What is the Chi Square Sum (rounding to 3 significant figures) for Purple versus White cross. The answer is 0.391

    But when I try to get this answer I use the formula (O-E)^2/E and get .09768 for Purple and .0048 for White which equals .1085



    Third part of the question:

    Using the following web site: (http://www.graphpad.com/quickcalcs/PValue1.cfm)
    What is the P-value (rounding to 3 significant figures) for Purple versus White cross.
     
    Last edited: Feb 26, 2010
  2. jcsd
  3. Feb 26, 2010 #2

    collinsmark

    User Avatar
    Homework Helper
    Gold Member

    Hello sonyab523,

    Welcome to Physics Forum!

    Btw, next time you might wish to put this sort of question in the
    Physics Forums > Science Education > Homework & Coursework Questions > Other Sciences
    category. 'Mostly just introductory physics here.

    But anyway, I think I can help (I'm not an expert in genetics, but I'm not completely unfamiliar with it either):

    Okay, here is where I believe you went wrong. The Expected White is 0.25 x 929 = 232.25.

    In other words, 3/4 of this population is expected to be Purple, 1/4 White.

    That makes the (O - E) for White -8.25.

    Your Purple calculation is the same as mine. After you make the above correction for White (and recalculate), I think you should be good to move forward.
     
  4. Feb 26, 2010 #3


    I see I forgot to round. I have another question on a similar problem but I'll post start another thread in the right forum. Thank you.
     
  5. Feb 26, 2010 #4

    collinsmark

    User Avatar
    Homework Helper
    Gold Member

    I was sort of under the impression that it's not a matter of rounding. What I assumed was that Purple and White represent a monohybrid cross between two heterozygotes. This is based more on theory, rather than on the measured statistics of the particular problem. I was assuming that the problem assumes one dominant phenotype (F1 phenotype), and one recessive (F2 phenotype). If my assumption was correct, it seems obvious here that Purple would be the dominant trait, call it "P", and White is the recessive trait, call it "w". Then there are only 4 possible combinations:

    PP
    Pw
    wP
    ww

    But since Purple is dominant trait, any combination with a P in it will show the characteristics of purple. So PP, Pw, and wP all produce Purple characteristic -- that's an expected 3/4 of the population. Only the ww combination produces a White characteristic. 1/4 of the population.

    [Edit] Or maybe to put it better, 3/4 and 1/4 of the total number of possible combinations.
     
    Last edited: Feb 26, 2010
Know someone interested in this topic? Share this thread via Reddit, Google+, Twitter, or Facebook




Similar Discussions: Chi square Dominant phenotype problem
  1. Least-squares problem (Replies: 0)

Loading...