Common Cold Virus Suppresses COVID-19

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    Cold Covid-19 Virus
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Discussion Overview

The discussion revolves around the potential interaction between the common cold virus (HRV) and SARS-CoV-2, specifically exploring whether HRV can suppress COVID-19 infection. The scope includes theoretical implications of viral interference and the dynamics of respiratory infections.

Discussion Character

  • Exploratory
  • Debate/contested
  • Conceptual clarification

Main Points Raised

  • One participant shares research findings indicating that HRV can suppress the replication of SARS-CoV-2 in human respiratory cell cultures, suggesting a potential protective effect of the common cold virus against COVID-19.
  • Another participant expresses caution about the implications of this interaction, noting the ongoing evolution of SARS-CoV-2 and the potential risks of manipulating viral dynamics.
  • A different viewpoint introduces the concept of viral interference, suggesting that seasonal infections tend to alternate rather than co-occur, which may indicate a broader phenomenon affecting viral infections.
  • Some participants express a lighthearted attitude towards the topic, with one reiterating a willingness to prefer a cold over COVID-19.
  • There is a mention of humor in the discussion, with one participant commenting on the tone of the conversation.

Areas of Agreement / Disagreement

Participants express a mix of excitement and caution regarding the implications of HRV's interaction with SARS-CoV-2. There is no consensus on the broader implications or the safety of such interactions, indicating ongoing debate.

Contextual Notes

The discussion includes assumptions about viral behavior and the potential consequences of viral interactions, which remain unresolved. The implications of viral interference and the impact of current public health measures on seasonal infections are also noted but not fully explored.

Who May Find This Useful

Readers interested in virology, infectious diseases, and the dynamics of respiratory infections may find this discussion relevant.

Tom.G
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I'll trade a cold for Covid-19 any time!

https://www.medicalnewstoday.com/articles/a-common-cold-virus-may-help-fight-covid-19

To find out, the researchers infected cultures of human respiratory cells in the lab with either SARS-CoV-2, an HRV, or both viruses at the same time.

The cultures closely mimicked the outer layer of cells, called the epithelium, that lines the airways of the lungs.

SARS-CoV-2 steadily multiplied in the cells that the team had infected with this virus alone. However, in cells also infected with HRV, the number of SARS-CoV-2 virus particles declined rapidly until they were undetectable just 48 hours after the initial infection.

In further experiments, the scientists found that HRV suppressed the replication of SARS-CoV-2, regardless of which virus infected the cells first.

Cheers,
Tom
 
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Well. I do understand the excitement, but with already observing the drift of the Sars-CoV-2, I'm not really sure we should force events which may result in a shift :nb)
 
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This might be an early indicator of the rather strange phenomena of viral interference, it seems like most seasonal infections take turns at infecting the population rather than occurring together. It seems that the effects of a viral infection causes changes in the internal environment that effectively inhibits other viruses causing infection at the same time.
https://academic.oup.com/jid/article/212/11/1690/2911897
 
Tom.G said:
I'll trade a cold for Covid-19 any time!
With all the distancing, there's no flu going around. I guess it's the same with colds.
 
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Somebody just made a joke out of the topic. :oldgrumpy:
 

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