Using the comparison test requires comparing the series in question with a known divergent series. To determine divergence, it's essential to confirm that the series, such as ∑(√[n]2 - 2), diverges. The Nth Term Test for Divergence can also be applied, where if the limit of the terms does not approach zero, the series diverges. It's important to note that the comparison must involve positive terms, as negative terms invalidate the direct comparison test. Absolute values can be used to establish convergence with a known absolutely convergent series.