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fordi1
Can someone help me to understand why juxta medulair néphron is implied in génération of cortico papilar gradient
Cortical nephrons are located in the outer region of the kidney and have a shorter loop of Henle, while juxta medullary nephrons are located near the medulla and have a longer loop of Henle. This difference allows for different functions and roles in kidney filtration and urine concentration.
Cortical nephrons make up about 80-85% of the total nephrons in the kidney, while juxta medullary nephrons make up the remaining 15-20%. This difference in abundance is due to the different functions and contributions of each type of nephron to kidney function.
Cortical nephrons have a higher glomerular filtration rate (GFR) compared to juxta medullary nephrons, meaning they are more efficient in filtering blood and producing urine. Juxta medullary nephrons, on the other hand, have a higher concentration ability and are responsible for producing concentrated urine through the process of countercurrent multiplication in the loop of Henle.
In addition to differences in location, loop of Henle length, and filtration capabilities, cortical and juxta medullary nephrons also have different blood supply. Cortical nephrons receive blood from the peritubular capillaries, while juxta medullary nephrons receive blood from the vasa recta. This difference in blood supply also contributes to their different functions in the kidney.
Both cortical and juxta medullary nephrons work together to maintain overall kidney function. While they have different roles and contributions, they are interconnected and rely on each other to maintain homeostasis and regulate body fluid balance. Disruption or dysfunction in one type of nephron can affect the function of the other and overall kidney function.