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Help in understanding effect size in fMRI

  1. Dec 6, 2016 #1
    Hello everyone, I'm a student of a Master's degree in Neuroscience and I'm preparing a journal club presentation on an article called "Differential extrageniculostriate and amygdala responses to presentation of emotional faces in a cortically blind field". I'm struggling to understand some of the results, in particular what a negative effect size means in fMRI. Is there someone that can explain that to me? I'm referring in particular to this picture of the paper https://d1gqps90bl2jsp.cloudfront.net/content/brain/124/6/1241/F4.large.jpg?width=800&height=600&carousel=1 [Broken]the one attached).
    What can I say about the "unseen CS-"? Why is it so negative? Does it mean that the amygdala has a very low degree of activation?
    Thanks to anyone that can help me :)
     

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    Last edited by a moderator: May 8, 2017
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  3. Dec 6, 2016 #2

    jim mcnamara

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    Staff: Mentor

    This appears to be something @DiracPool could help with. I'm confused with your explanation as well. fMRI mesures blood flow in the brain which indirectly shows which brain tissues are active. Interpretation is, IMO, sometimes a bit subjective. Each area seems to require the reader to be in the know how the ground rules are applied. My opinion only. In particular you have to have a solid grip on the particular known aspects of certain kinds of responses.
     
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