Could Two Mules with Down's Syndrome Successfully Breed?

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SUMMARY

Mules possess 63 chromosomes and are inherently sterile due to their chromosomal structure. The discussion explores the hypothetical scenario of two mules with Down's syndrome, which would have 64 chromosomes. However, it is established that even with an additional chromosome, mules would likely remain infertile because the chromosomal imbalance does not guarantee successful reproduction. The condition known as Down syndrome is specifically caused by the non-disjunction of an entire chromosome, commonly referred to as trisomy 21.

PREREQUISITES
  • Understanding of chromosomal structures and their implications on fertility
  • Knowledge of Down syndrome and its genetic causes
  • Familiarity with the concept of non-disjunction in genetics
  • Basic principles of animal reproduction and hybrid sterility
NEXT STEPS
  • Research the genetic implications of hybrid animals, specifically mules
  • Study the mechanisms of non-disjunction and its effects on chromosome number
  • Explore the genetic basis of Down syndrome and its variations
  • Investigate cases of animal fertility and chromosomal abnormalities
USEFUL FOR

Geneticists, veterinarians, biologists, and anyone interested in the genetics of hybrid animals and chromosomal disorders.

jimmy p
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OK, i probably know the answer to this. Mules have 63 chromosomes, and are sterile. Is this BECAUSE they have 63 chromosomes?? If so, if you had two mules with Down's syndrome (so they have 64 chromosomes) would they be able to successfully breed?
 
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Down syndrome is caused by a none disjunction at one gene not the entire chromosome.

Nautica
 
I thought it was an entire copy of another chromosome, which is why it was called sticky chromosome syndrome...
 
Nautica you are wrong, is the non-disjunction of entire chromosome. The other name for down syndrom is trisomie 21.

Anyway Jimmy, a mule with down syndrom would probably still be infertile because the excess chromsome migth not be the one missing. Therefore you get a chromosome in triplicate and one in single.
 
Yes, I just looked it up.

thanks, nautica
 
thanx that was the answer i was expecting anyway, just had a surprise, i thought about something (if only briefly) :smile:
 

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