Covid-19 Neurological and Psychological sequelae

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SUMMARY

The study titled "6-month neurological and psychiatric outcomes in 236,379 survivors of COVID-19: a retrospective cohort study using electronic health records" provides definitive evidence of significant neurological and psychiatric morbidity in the six months following COVID-19 infection. The highest risks were observed in patients with severe cases of the virus. This research underscores the necessity for further investigation into the long-term medical consequences of COVID-19, particularly through complementary study designs such as prospective cohorts. The findings are crucial for effective service planning and prioritizing future research efforts.

PREREQUISITES
  • Understanding of COVID-19 infection and its clinical implications
  • Familiarity with retrospective cohort study methodologies
  • Knowledge of neurological and psychiatric morbidity
  • Experience with electronic health records analysis
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  • Research prospective cohort study designs in medical research
  • Explore the long-term effects of viral infections on mental health
  • Investigate neurological assessments post-COVID-19 infection
  • Study service planning strategies for post-COVID healthcare
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Healthcare professionals, researchers in neurology and psychiatry, public health planners, and anyone involved in post-COVID patient care and research initiatives.

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TL;DR
Approximately 30% of Covid patients had mild to major neurological and psychological deficits in a retrospective research project using data from a cohort of 236379
Interpretation
Our study provides evidence for substantial neurological and psychiatric morbidity in the 6 months after COVID-19 infection. Risks were greatest in, but not limited to, patients who had severe COVID-19. This information could help in service planning and identification of research priorities. Complementary study designs, including prospective cohorts, are needed to corroborate and explain these findings.

This is a preliminary 'long haul' investigation, which appears to warrant further research into the medical consequences of Covid-19 patients after going home post-disease.

"6-month neurological and psychiatric outcomes in 236 379 survivors of COVID-19: a retrospective cohort study using electronic health records"

  • Maxime Taquet, PhD
  • Prof John R Geddes, MD
  • Prof Masud Husain, FRCP
  • Sierra Luciano, BA
  • Prof Paul J Harrison, FRCPsych
Open Access Published: April 06, 2021 DOI: https://doi.org/10.1016/S2215-0366(21)00084-5
 
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This is an incredibly important and timely study, given the severe impact of the COVID-19 pandemic on our society. It's great to see that this study has been conducted to try and better understand the long-term effects of the virus. The findings suggest that there is a high risk of neurological and psychiatric morbidity for those who have survived COVID-19, especially for those with severe cases. This information could be very useful for service planning and for identifying research priorities. I think more research is needed to corroborate and explain these findings, such as through prospective cohorts.
 

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