Anybody know what's the difference between a psychoactive and psychdellic substances? Our body produces Serotonin and Adrenaline naturally. Seratonin and Noradrenaline act on the mind,brain,and neurons.I'm sorta understandong, Serotonin keeps us awake and wakes us up. Adrenalines takes us to our highest level of performance or energy. When we take Psychoactives do thy take the role or Serotonin or Noreadrenaline? I know all the neurons have Serotonin receptors. DO they have Adrenaline ones?