DNA Sequence for Anti-Sense Strand of CCUAGGCUA mRNA Molecule

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SUMMARY

The anti-sense strand of the DNA corresponding to the mRNA sequence CCUAGGCUA is GGATCCGAT. This sequence is derived by replacing uracil (found in RNA) with thymine (found in DNA) and reversing the mRNA sequence to align with the 3' to 5' directionality of the anti-sense strand. The discussion confirms that the anti-sense strand serves as the coding strand for mRNA synthesis, and emphasizes the importance of understanding base pairing conventions in nucleic acids.

PREREQUISITES
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  • Knowledge of base pairing rules (A-T, G-C, U-A)
  • Familiarity with transcription processes in molecular biology
  • Basic grasp of 3' and 5' strand orientation
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  • Investigate the role of complementary base pairing in genetic coding
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A portion of an mRNA molecule has the sequence CCUAGGCUA. What is the sequence of the anti sense strand of the corresponding DNA molecule?

The anti sense strand is the coding strand. The 3' to 5' strand from which mRNA builds. Does that mean the sequence would be backwards?
 
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Coco12 said:
A portion of an mRNA molecule has the sequence CCUAGGCUA. What is the sequence of the anti sense strand of the corresponding DNA molecule?

The anti sense strand is the coding strand. The 3' to 5' strand from which mRNA builds. Does that mean the sequence would be backwards?

First part: write out your reasoning for thinking that.

2nd part: are all bases the same in RNA and DNA?
 
epenguin said:
First part: write out your reasoning for thinking that.

2nd part: are all bases the same in RNA and DNA?

RNA has uracil instead of thymine

So it would the complementary base pairs : GGATCCGAT?
 
Coco12 said:
RNA has uracil instead of thymine

Right.

Coco12 said:
So it would the complementary base pairs : GGATCCGAT?

are you unsure? This is not for a guess, just a test of knowing how mRNA is synthesised, and the conventions. Do a little picture if nec and don't be afraid to attach 3' and 5' signs to your strand ends.
 
epenguin said:
Right.
are you unsure? This is not for a guess, just a test of knowing how mRNA is synthesised, and the conventions. Do a little picture if nec and don't be afraid to attach 3' and 5' signs to your strand ends.

Just to clarify if the question said sense strand instead of anti , it would be the same sequence given except it would have thymine instead of uracil right?
 
Coco12 said:
RNA has uracil instead of thymine

So it would the complementary base pairs : GGATCCGAT?

Is that the sequence complementary to the mRNA?

Coco12 said:
Just to clarify if the question said sense strand instead of anti , it would be the same sequence given except it would have thymine instead of uracil right?

yes I think that's a correct deduction.
 

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