Do Semi-Porous Transparent Membranes for Glucose Transport Exist?

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Discussion Overview

The discussion centers around the existence and literature related to semi-porous transparent membranes that can selectively allow glucose to pass in one direction. Participants explore the potential applications of such membranes, including their use in contact lenses and in the context of glucose transport in biomedical applications.

Discussion Character

  • Exploratory
  • Technical explanation
  • Debate/contested

Main Points Raised

  • One participant questions whether such a membrane exists, noting that in dialysis, glucose typically passes through membranes in both directions, driven by concentration gradients.
  • Another participant mentions ultrafiltration and electrodialysis as processes where membranes may allow selective passage based on molecular weight or charge.
  • Some participants suggest looking into literature related to the encapsulation of Islet cells as a potential source of information on relevant membranes.
  • There is a discussion about the possibility of starting experiments with dialysis tubing, although it does not meet the criteria of allowing glucose to move in only one direction.

Areas of Agreement / Disagreement

Participants express differing views on the existence of membranes that allow unidirectional glucose transport, with some asserting that such membranes do not exist while others suggest exploring related literature for potential solutions.

Contextual Notes

The discussion highlights uncertainties regarding the specific properties and applications of membranes, as well as the limitations of existing technologies like dialysis and ultrafiltration in achieving the desired selective transport of glucose.

Who May Find This Useful

Researchers and students interested in membrane technology, glucose transport mechanisms, and biomedical applications may find this discussion relevant.

Rhydo
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Hi!

My friends and I have been working on a project which encapsulates the use of semi porous transparent membranes that can selectively pass glucose molecules through them in one direction.

Does such a membrane already exist? Where can I get literature on the construction and/or existence of such materials? Also are such membranes used in contact lenses?

Any help would be appreciated.
 
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Rhydo said:
Hi!

My friends and I have been working on a project which encapsulates the use of semi porous transparent membranes that can selectively pass glucose molecules through them in one direction.

Does such a membrane already exist? Where can I get literature on the construction and/or existence of such materials? Also are such membranes used in contact lenses?

Any help would be appreciated.

Basically I think such a thing does not exist.
In dialysis substances like glucose pass through a membrane in both directions. But the result is that more will pass from the side where it is more concentrated to the side where it is less.
Then there is ultrafiltration where solvent passes through a membrane under pressure. Low MW molecules go with it and higher MW do not pass the membrane.

So on a molecular weight basis some molecules can pass slower than others. Probably there are membranes more specific about what they pass, particularly on basis of charge.

There is also electrodialysis.

Have a look at the commercial literature, brochures etc.
 
epenguin said:
Basically I think such a thing does not exist.
In dialysis substances like glucose pass through a membrane in both directions. But the result is that more will pass from the side where it is more concentrated to the side where it is less.

Thanks for that! We were actually looking for something that would allow glucose to move in just one direction. So 'dialysis tubing' was something that we were looking into. Now I suppose we can start with some experiments!
 
chemisttree said:
A good place to look is in the literature related to the encapsulation of Islet cells.

I had no idea about this field. Thanks! This helped a lot!
 

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