Electrophysiology Quick Homework Problems

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SUMMARY

The discussion focuses on solving two electrophysiology homework problems related to an RC circuit and neuronal membrane properties. For the first problem, the voltage at time t = 2RC can be calculated using the equation V(t) = V(1 - e^(-t/RC)). The second problem involves calculating the resistance per cm² of a neuronal membrane, which is determined to be 1000Ω per cm² based on the given time constant and capacitance. Additionally, the number of ion channels per µm² can be derived once the total current is identified.

PREREQUISITES
  • Understanding of RC circuits and their time constants
  • Familiarity with the equation V(t) = V(1 - e^(-t/RC))
  • Knowledge of conductance and capacitance in neuronal membranes
  • Basic principles of current calculation in electrical circuits
NEXT STEPS
  • Study the derivation and application of the equation V(t) = V(1 - e^(-t/RC)) in RC circuits
  • Learn how to calculate total current in a circuit with multiple ion channels
  • Explore the relationship between conductance, resistance, and capacitance in biological membranes
  • Investigate the implications of ion channel density on neuronal excitability
USEFUL FOR

Students in electrophysiology, electrical engineering, and neuroscience, particularly those tackling problems related to RC circuits and neuronal membrane properties.

wubwubs
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Homework Statement


Hi guys,
I've been trying to solve these two questions for the last hour and can't seem to find the solution, any help would be very much appreciated. :smile:

1. An RC circuit is given a step voltage (charging) of V at t = 0 seconds. What is the value of voltage at t = 2RC?

2. If the conductance of a single ion channel is 1pS and its capacitance per cm2 is 1mF and the time constant for a human neuron is 1ms:
(a) What is the resistance per cm2 of a neuronal membrane?

(b) How many ion channels on average must there be in one µm2 of neuronal membranes?

Homework Equations


T = RC
Tau = Resistor x Capacitor

The Attempt at a Solution


1. Tried attempting this question for a solid hour and not sure where to begin.
2.
(a) 1 x 10^-3ms = R x (1 x 10^-6F)
R = 1000W per cm2
(b) I know to divide the total current by the single current but I can't seem to find the solution to identify the total current.
 
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wubwubs said:

Homework Statement


Hi guys,
I've been trying to solve these two questions for the last hour and can't seem to find the solution, any help would be very much appreciated. :smile:

1. An RC circuit is given a step voltage (charging) of V at t = 0 seconds. What is the value of voltage at t = 2RC?

2. If the conductance of a single ion channel is 1pS and its capacitance per cm2 is 1mF and the time constant for a human neuron is 1ms:
(a) What is the resistance per cm2 of a neuronal membrane?

(b) How many ion channels on average must there be in one µm2 of neuronal membranes?

Homework Equations


T = RC
Tau = Resistor x Capacitor

The Attempt at a Solution


1. Tried attempting this question for a solid hour and not sure where to begin.
2.
(a) 1 x 10^-3ms = R x (1 x 10^-6F)
R = 1000W per cm2
(b) I know to divide the total current by the single current but I can't seem to find the solution to identify the total current.
Welcome to the PF.

On question -1-, what is the equation for v(t) for an RC circuit that starts charging at t=0? You are correct that the time constant is RC, but how is that used in the actual equation?
 
berkeman said:
Welcome to the PF.

On question -1-, what is the equation for v(t) for an RC circuit that starts charging at t=0? You are correct that the time constant is RC, but how is that used in the actual equation?

Hi and thank you for the reply,
I believe the equation is V(t) = V(1-e^-t/RC). If you require additional information please ask, and thank you for the help.
 
Assuming the equation is correct, any particular reason to not just plug t=2RC into?
 

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