Direct experiments to determine the mean free path of gas molecules, rather than their distribution, are challenging but possible. While many methods exist for measuring the average mean free path in large collections, a more specific approach is suggested using low partial pressures of atoms that can be optically excited. By observing collisional effects during laser cooling of trapped atoms, researchers could infer information about the mean free path. Such experiments have parallels in the liquid phase, indicating potential for similar methodologies in gases. Overall, innovative experimental designs could yield insights into the mean free path of individual gas molecules.