Expert Answer: The Importance of Research and Self-Learning in Asking Questions

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Discussion Overview

The discussion revolves around the binding interactions between DNA, RNA, and proteins, exploring the mechanisms by which these biomolecules interact. It touches on the differences in composition and structure among these molecules and seeks to understand the nature of their binding relationships.

Discussion Character

  • Exploratory
  • Technical explanation
  • Debate/contested

Main Points Raised

  • One participant asks how DNA, RNA, and proteins bind together, noting the differences in their structures and components.
  • Another participant suggests that the original poster should conduct preliminary research before asking questions.
  • A participant explains that amino acids can interact with nucleotides, detailing various mechanisms such as hydrogen bonding, interactions with the sugar phosphate backbone, and pi-pi stacking.
  • Some participants express frustration with the expectation for members to ask well-researched questions, arguing that the forum should support inquiries from those seeking to learn.
  • It is noted that "cold" questions, or those lacking prior research, can lead to misunderstandings and wasted effort in providing detailed answers.

Areas of Agreement / Disagreement

Participants express differing views on the appropriateness of the original question, with some advocating for more self-research before posting, while others defend the value of asking questions regardless of prior effort. The discussion remains unresolved regarding the expectations for question-asking in the forum.

Contextual Notes

There are indications that the discussion may be influenced by varying interpretations of what constitutes a well-formulated question and the balance between self-learning and seeking help.

hivesaeed4
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How do DNA, RNA and Proteins bind together? I mean Dna and rna differ in uracil and thymine bases along with the sugars but both differ from proteins in the fact that proteins are made up of amino acids whereas dna and rna are made up of nucleotides. So how do they bind to each other?
 
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Amino acids are perfectly capable of interacting with nucleotides. Proteins can interact with nucleic acids in a variety of ways. Many proteins that interact with double-stranded DNA insert a helix into the major groove of the DNA where the amino acid residues can recognize specific bases through hydrogen bonding interactions. Interactions can also occur with between positively-charged residues on the protein and the negatively-charged sugar phosphate backbone of the nucleic acids. Proteins can also interact with the bases through pi-pi stacking or cation-pi interactions.
 
Ryan_m_b said:
Please try to do a cursory google before asking a question

What?! I thought I had this webite figured out. I thought the preferred paradigm was inexpert person asks question - expert provides answer. It seemed like quite an advanced question to me. If that question is not up to standard then what on Earth is this forum for?
 
Ken Natton said:
What?! I thought I had this webite figured out. I thought the preferred paradigm was inexpert person asks question - expert provides answer. It seemed like quite an advanced question to me. If that question is not up to standard then what on Earth is this forum for?
ZapperZ has a good blog post about this https://www.physicsforums.com/blog.php?b=3588

Essentially we prefer members not to ask "cold" questions, i.e. they demonstrate that they have not done any effort to find an answer before coming here. The reason we prefer this is twofold:

1) If someone becomes reliant on just asking PF questions and getting an answer rather than trying to find something out and learn themselves then they are missing out on learning vital skills. Obviously we want people to ask questions but there has to be a mix with self learning. We do not exist as a one stop teaching service.

2) Often cold questions are quite vague yet the OP is looking for a specific answer. This can waste members time as they begin to give an answer in great detail only to have the OP disregard most of it and focus on the specific they want. If you've seen threads like this you may have seen that they become extremely frustrating for all involved (especially if the OP has some idea in mind they are trying to justify).
 
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