To find an orthogonal vector in 3D, the dot product can be utilized by setting <v,c> equal to zero, allowing for the selection of arbitrary values for two components and solving for the third. For example, given vector v = (4,2,3), one can choose x=0 and y=-3 to find c = (0,-3,2). Alternatively, the cross product can be used by selecting a non-parallel vector p to compute c = v x p, resulting in another orthogonal vector. There are infinitely many orthogonal vectors in 3D, and simple tricks similar to those in 2D can be applied, although achieving a unit vector may require more complex calculations. Overall, while there are efficient methods to find orthogonal vectors, the need for unit vectors introduces additional computational considerations.