Glucose Heating w/ HI: Why Get N-Hexane? | Reaction Explanation

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SUMMARY

The discussion centers on the reaction of glucose with hydroiodic acid (HI) leading to the formation of n-hexane. This process involves a reduction mechanism where HI is oxidized to iodate. The reaction is notable for its application in the synthesis of methamphetamine, as depicted in the television series "Breaking Bad." This mechanism is recognized as a common topic in introductory organic chemistry courses.

PREREQUISITES
  • Understanding of organic chemistry reaction mechanisms
  • Familiarity with hydroiodic acid (HI) and its properties
  • Knowledge of reduction and oxidation processes
  • Basic concepts of carbohydrate chemistry, specifically glucose
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  • Research the detailed mechanism of glucose reduction with hydroiodic acid
  • Study the synthesis pathways of methamphetamine in organic chemistry
  • Explore the role of iodate in oxidation-reduction reactions
  • Learn about carbohydrate transformations in organic synthesis
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Students and professionals in organic chemistry, particularly those interested in reaction mechanisms, carbohydrate chemistry, and synthetic pathways in pharmaceuticals.

erisedk
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Why does glucose on prolonged heating with HI give n-hexane?
What mechanism/reaction type is this? All I knew till now was that alcohols would give halogen substituted products with hydrogen halides.
 
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It's a reduction with hydroiodic acid being oxidized to iodate. Btw the same reaction is used in the synthesis of methamphetamine in beeaking bad.
 
Is it a common mechanism in introductory organic chemistry?
 

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