Hemoglobin S Trait: Healthy Carrier?

[Soaring Crane]

If a person is a carrier for sickle cell disease or has hemoglobin AS, then does this mean that the carrier is not affected by hemoglobinopathy? (He/she is normal/healthy?)

Thank you.

 

[epenguin]

If a person is a carrier for sickle cell disease or has hemoglobin AS, then does this mean that the carrier is not affected by hemoglobinopathy? (He/she is normal/healthy?)

Thank you.

Yes, or healthy enough. And surely you have or will come across the story of why they are HEALTHIER than people with only A in certain environments, explaining why S became as common as it did?

 

[Soaring Crane]

Thanks, epenguin. Yes, they are protected from malaria?

 

[epenguin]

Thanks, epenguin. Yes, they are protected from malaria?

That's right. Suggesting that 'healthy' is often only relative to an environment. (And sometimes to other genetic background).
I can't say whether they may not have some slight disadvantage away from the malarial environments.