Cotransport, also known as secondary active transport, is a process that enables cells to move substances against their concentration gradient by coupling their transport to the movement of another molecule that is moving down its gradient. This mechanism is crucial for nutrient uptake, such as glucose, even when its concentration is lower outside the cell. Active transport requires energy, which can be supplied directly by ATP or indirectly by linking the transport of one molecule to another. For instance, sodium-glucose transporters utilize the favorable movement of sodium ions into the cell, which occurs due to a higher concentration of sodium outside the cell, to drive the unfavorable transport of glucose into the cell. An analogy illustrates this concept: just as a guy can gain entry to a crowded frat party by bringing girls along, glucose can enter the cell by hitching a ride with sodium ions. This process is essential for cellular function and nutrient acquisition.