How does LSD impact the brain and body?

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Julio R
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I don't know if this is the right subforum, but I have a question about LSD. First of, I do not take drugs. I'm trying to explain it to a friend.

What are the positive (if any) and negative effects on your brain and body when on LSD?

I looked online, but only found forums with a lot of bias. I prefer a scientific perspective.
 
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Thank you both very much. Very helpful links.