mktsgm
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- TL;DR Summary
- How does the body behave in terms of insulin response due to cortisol induced gluconeogenesis?
Cortisol normally initiates gluconeogenesis especially in the mornings,
1. Glucose rises due to liver gluconeogenesis.
2. Does insulin production respond to this glucose rise?
3. If it entails insulin production (due to rise in glucose), liver might store it back as glycogen leading to a futile cycle.
4. If it does not entail insulin production, the other insulin sensitive cells such as skeletal muscle cells might suffer for want of GLUT4 expression and glucose uptake.
How does the body behave (in terms of insulin response) due to cortisol induced gluconeogenesis?
How does the body ensure supply of glucose to skeletal muscle cells at the same time ensuring liver does not undergo futile glycogenesis, due to insulin response?
1. Glucose rises due to liver gluconeogenesis.
2. Does insulin production respond to this glucose rise?
3. If it entails insulin production (due to rise in glucose), liver might store it back as glycogen leading to a futile cycle.
4. If it does not entail insulin production, the other insulin sensitive cells such as skeletal muscle cells might suffer for want of GLUT4 expression and glucose uptake.
How does the body behave (in terms of insulin response) due to cortisol induced gluconeogenesis?
How does the body ensure supply of glucose to skeletal muscle cells at the same time ensuring liver does not undergo futile glycogenesis, due to insulin response?