How to Interpret Drosophila Genetics Problem with Red and White Eye Traits?

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Discussion Overview

The discussion revolves around the inheritance patterns of eye color traits in Drosophila, specifically focusing on red and white eye traits. Participants are analyzing data from crosses between red-eyed females and white-eyed males, exploring the implications of sex-linked inheritance and the nature of the alleles involved.

Discussion Character

  • Exploratory
  • Debate/contested
  • Technical explanation

Main Points Raised

  • One participant presents data from a cross between red-eyed females and white-eyed males, noting that all F1 females were white-eyed and all F1 males were red-eyed.
  • Another participant challenges the assumption that the white eye trait is sex-linked recessive, suggesting that the data may indicate a different mode of inheritance.
  • A participant expresses confusion about the mode of inheritance and requests hints for clarification.
  • There is a suggestion to reconsider whether the trait is sex-linked or autosomal and to test both recessive and dominant assumptions.
  • One participant insists that the data suggests a sex-linked recessive trait, yet the pedigree chart does not align with this assumption, indicating a potential misunderstanding or oversight.
  • A later reply proposes that the white eye trait could be a sex-linked dominant trait, prompting participants to reassess their expectations based on this new perspective.

Areas of Agreement / Disagreement

Participants do not reach consensus on the mode of inheritance for the white eye trait, with multiple competing views remaining regarding whether it is sex-linked recessive or possibly sex-linked dominant.

Contextual Notes

Participants express uncertainty regarding the assumptions made about the inheritance patterns, and there are unresolved questions about the accuracy of the pedigree chart based on the presented data.

fishingspree2
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Hello,

I want to study the inheritance of red eyes and white eyes in drosophila.
I have mated red-eyed females with white eyed males.

F1: All F1 females were white eyed and all F1 males were red-eyed.
19 white eyed females and 22 red eyed males.

I have also crossed the females and males of the F1 generation, but this is not relevant for my question.

I am trying to draw a pedigree chart for the P generation and their offspring, but there is a small problem. I know that this trait is sex-linked, and that the white eyes allele is recessive. Let R denote the red eyes allele and r the white eyes allele. Here is what I get:
16m3vrc.jpg

Please, what is the problem?
 
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You are correct, these data are clearly inconsistent with the white eye trait being a sex-linked recessive trait. These data are consistent, however, with a different type of inheritance for the white eye trait. Can you determine what this mode of inheritance is?
 
Hmm I don't really see what mode of inheritance it could be... can you give me a hint?
 
Well, first consider whether it is sex-linked or not. Do the data suggest that it is sex-linked? Once you figure out whether it is sex-linked or autosomal, you can try assuming that it is recessive and see whether the results match, then try assuming its dominant.
 
I have tried sex-linked and it didn't work. The data suggests it is sex-linked, and I know that answer is recessive sex-linked. Recessive sex-linked is what I tried and it didnt work. I think I am missing something... please help me

EDIT: By the way, the method I have tried is assuming the inheritance mode is sex-linked. Maybe I should have put R as an exponent

EDIT2: After re-reading your post it seems like you've understood my try of the white eye being a sex-linked recessive trait. This is what the data suggests. However, the pedigree does not work, and I thought after reading on wikipedia that it was indeed a sex-linked recessive trait. I am lost
 
Last edited:
Assume white eyes are a sex-linked dominant trait. In your red-eyed female x white-eyed male cross, what would you expect?

Now, the white eyed trait is normally a recessive sex-linked trait. Is this problem from a class or did you actually do this experiment and get this data?
 

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